Decarboxylation
Decarboxylation is the chemical process of applying heat to cannabis to activate its cannabinoids. Raw cannabis contains THCA and CBDA, which are non-intoxicating. When heated (through smoking, vaping, or oven-baking at 220-245°F for 30-45 minutes), these acids lose a carboxyl group and convert to active THC and CBD. Decarboxylation is essential for making edibles and tinctures.